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  • January 22, 2026

Pioglitazone Safety: Heart Failure, Edema, and Bladder Risks Explained

Pioglitazone Safety: Heart Failure, Edema, and Bladder Risks Explained

Pioglitazone (ACTOS) helps control blood sugar in type 2 diabetes but carries serious risks: heart failure, swelling in legs and feet, and increased bladder cancer risk with long-term use. Learn who should avoid it and what safer alternatives exist.

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